狗脊多糖調(diào)控lncRNA NEAT1延緩椎間盤終板軟骨細(xì)胞衰老的作用研究
風(fēng)濕病與關(guān)節(jié)炎
頁數(shù): 5 2024-02-28
摘要: 目的:探討狗脊多糖通過調(diào)節(jié)lncRNA NEAT1延緩椎間盤終板軟骨細(xì)胞衰老的作用機(jī)制。方法:將15只C57BL/6小鼠的椎間盤終板軟骨細(xì)胞進(jìn)行體外培養(yǎng);經(jīng)10 ng·mL
-1白細(xì)胞介素-1β(IL-1β)干預(yù)24 h誘導(dǎo)軟骨細(xì)胞;將軟骨細(xì)胞隨機(jī)分為空白對(duì)照組、模型對(duì)照組(10 ng·mL
-1 IL-1β)和狗脊多糖各劑量組(100,200,400μg·mL~(-1... (共5頁)